Pathogenic outcome following experimental infection of sheep with Chlamydia abortus variant strains LLG and POS
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چکیده
منابع مشابه
Pathogenic outcome following experimental infection of sheep with Chlamydia abortus variant strains LLG and POS
This study investigated the pathogenesis of two variant strains (LLG and POS) of Chlamydia abortus, in comparison to a typical wild-type strain (S26/3) which is known to be responsible for late term abortion in small ruminants. Challenge with the three strains at mid-gestation resulted in similar pregnancy outcomes, with abortion occurring in approximately 50-60% of ewes with the mean gestation...
متن کاملSeroprevalence of Chlamydia abortus infection in sheep and goats in Iran
BACKGROUND: Chlamydia abortus is a zoonotic bacteriumthat commonly causes abortions in ruminants. This microorganismis one of the most important infectious agents causingabortion and major economic losses in sheep and goats worldwide.OBJECTIVES: The objective of this study was investigatingthe status of C. abortus infection among small ruminantflocks of some regions in Iran. METHODS: A total of...
متن کاملGenome sequence of the Chlamydophila abortus variant strain LLG.
Chlamydophila abortus is a common cause of ruminant abortion. Here we report the genome sequence of strain LLG, which differs genotypically and phenotypically from the wild-type strain S26/3. Genome sequencing revealed differences between LLG and S26/3 to occur in pseudogene content, in transmembrane head/inc family proteins, and in biotin biosynthesis genes.
متن کاملIntranasal Infection with Chlamydia abortus Induces Dose-Dependent Latency and Abortion in Sheep
BACKGROUND Latency is a key feature of the animal pathogen Chlamydia abortus, where infection remains inapparent in the non-pregnant animal and only becomes evident during a subsequent pregnancy. Often the first sign that an animal is infected is abortion occurring late in gestation. Despite this, little is understood of the underlying mechanisms that control latency or the recrudescence of inf...
متن کاملIn silico functional elucidation of uncharacterized proteins of Chlamydia abortus strain LLG
AIM This study reports structural modeling, molecular dynamics profiling of hypothetical proteins in Chlamydia abortus genome database. METHODOLOGY The hypothetical protein sequences were extracted from C. abortus LLG Genome Database for functional elucidation using in silico methods. RESULTS Fifty-one proteins with their roles in defense, binding and transporting other biomolecules were un...
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ژورنال
عنوان ژورنال: PLOS ONE
سال: 2017
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0177653